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All rights reserved. Number 8860726. Registered in England and Wales. coragen Arysta says the DuPont collaboration expands their development of proprietary foliar insecticides to protect specialty crops.

Chlorantraniliprole (DPX-E2Y45, Rynaxypyr(R), Coragen(R)) is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). chlorantraniliprole It has very low toxicity for mammals (both acute and chronic), high intrinsic activity on target pests, strong ovi-larvicidal and larvicidal properties, long lasting crop protection and no cross-resistance to any existing insecticide. Rapid excretion via bile (49-53%) within 48hr of dose. By activating the insect ryanodine receptors (RyRs) it stimulates the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species (Cordova et al. Development in Slovenia is currently focused in foliar applications in apples, potatoes and grapes. Cabbage loopers; Corn borers; Armyworms; Cutworms, Potatoes; Grapes; Cotton; Vegetables including artichoke, asparagus, bulb vegetables, corn, herbs, legumes, roots and tubers, EC Regulation 1107/2009 (repealing 91/414), Approved for use () under EC 1107/2009 in the following EU Member States, Canada; USA; Australia; Korea; New Zealand; Argentina; China; Chile; Colombia; Honduras; Indonesia; Vietnam, CC1=C(C(=CC(=C1)Cl)C(=O)NC)NC(=O)C2=CC(=NN2C3=C(C=CC=N3)Cl)Br, International Chemical Identifier key (InChIKey), International Chemical Identifier (InChI), InChI=1S/C18H14BrCl2N5O2/c1-9-6-10(17(27)22-2)15(12(21)7-9)24-18(28)13-8-14(19)25-26(13)16-11(20)4-3-5-23-16/h3-8H,1-2H3,(H,22,27)(H,24,28), Diamide insecticide; Pyridylpyrazole insecticide, EU dossier: acetonitrile <3 g kg; 3-picoline <3 g kg; methanesulfonic acid <2 g kg. Development in Slovenia is currently focused in foliar applications in apples, potatoes and grapes. It has a low aqueous solubility and a low volatility. Used to control a broad spectrum of pests on a range of crops including potatoes and cotton.



It is highly toxic to aquatic invertebrates, moderately toxic to birds and aquatic plants, and has a low toxicity to vbees and earthworms. This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them.



EU Annex III PIC DGD) (, R = Peer reviewed scientific publications, F = U.S. EPA ECOTOX database / U.S. EPA pesticide fate database / Miscellaneous WHO documents (, A = Chromosome aberration (EFSA database), E = Unspecified genotoxicity type (miscellaneous data source), US EPA Databases Related to Pesticide Risk Assessment, 2,6-dichloro-4-methyl-11H-pyrido(2,1-beta)quinazolin-11-one (Ref: IN-ECD73), 5-bromo-N-methyl-1H-pyrazole-3-carboxamide (Ref: IN-F6L99), 2-(3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl)-6-chloro-8-methyl-4(3H)-quinazoline (Ref: IN-GAZ70), 2-(3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazol-5-yl)-6-chloro-3, 8dimethyl-4(3H)-quinazolinone (Ref: IN-EQW78). The product general features have been presented in previous, referenced papers. Chlorantraniliprole has a low oral mammalian toxicity. The long-term agreement allows Arysta LifeScience to combine Rynaxypyr insect control in premixes with acetamiprid which creates novel insecticidal formulations which more efficiently and conveniently address growers pest control needs. Informa Markets, a trading division of Informa PLC. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Farm Progress is part of the Informa Markets Division of Informa PLC. Chlorantraniliprole (DPX-E2Y45, Rynaxypyr(R), Coragen(R)) is a new compound by DuPont belonging to a new class of selective insecticides (anthranilic diamides) featuring a novel mode of action (group 28 in the IRAC classification). Copyright 2022. 9th Slovenian Conference on Plant Protection (9. slovensko posvetovanje o varstvu rastlin), Nova Gorica (Slovenia), 4-5 March 2009.- 978-961-90950-7-2.- p. 39-46". Arysta LifeScience gains access to DuPonts Rynaxypyr mixtures, Awareness crucial for mental health intervention, Study looks at declining Oklahoma wild turkey population, Shrinking cattle herd could equal high calf, beef prices, Southwest cotton organizations report on crop status, Keep an eye out for algae overgrowth in ponds this summer, Peanut industry gathers to discuss progress, challenges ahead. Lewis, K.A., Tzilivakis, J., Warner, D. and Green, A. Allowed HTML tags:


. A broadened spectrum of Rynaxypyr control of sucking pests including aphids, whiteflies, some lepidoptera, and micro-lepidoptera; Provides a good fit for row and specialty crops; Offers a flexible application timing that works with IPM; and. Lines and paragraphs break automatically. The remarkably favourable toxicity profile of chlorantraniliprole, combined with the low use rates, provides large margins of safety for consumers and agricultural workers. After reviewing the product profile, results from laboratory, field and semi-field tests are provided. It tends to be highly persistent in the environment. The following alerts are based on the data in the tables below. Coragen(R) demonstrated excellent performance on codling moth and other chewing pests, stability of performance across the different conditions and minimal impact on pollinators, beneficial insects and predatory mites. Arysta LifeScience and DuPont Crop Protection will collaborate on the development of new foliar insecticides based on DuPont's market-leading product Rynaxypyr (chlorantraniliprole).

2006). After reviewing the product profile, results from laboratory, field and semi-field tests are provided. Whereas the new mode of action makes chlorantraniliprole a valuable option for IRM (Insecticide Resistance Management) strategies, safety to key beneficial arthropods and honeybees confer a strong fit within IPM (Integrated Production Management) programs. The product general features have been presented in previous, referenced papers.

Chlorantraniprole is a broad spectrum insecticide. The fundamental mission of the Biotechnical Faculty is to provide university level, advanced professional, and postgraduate education, as well as to carry out scientific research and technical and consulting work concerning the sciences of living nature (biology, microbiology) as well as agriculture, forestry and fisheries (forestry, animal husbandry, agronomy) and the related production technologies (wood technology, food technology, biotechnology). 2006). Web page addresses and e-mail addresses turn into links automatically. In the EU trials, rates of 10-60 g a.s./ha were highly effective on important pests such as: Cydia pomonella, Cydia molesta, Lobesia botrana, Eupoecilia ambiguella, Leptinotarsa decemlineata, Ostrinia nubilalis and Helicoverpa armigera. In the EU trials, rates of 10-60 g a.s./ha were highly effective on important pests such as: Cydia pomonella, Cydia molesta, Lobesia botrana, Eupoecilia ambiguella, Leptinotarsa decemlineata, Ostrinia nubilalis and Helicoverpa armigera. The common denominator of all academic and scientific disciplines at the Biotechnical Faculty i [], Chlorantraniliprole (DPX-E2Y45, Rynaxypyr(R), Coragen(R)), a new diamide inseticide for control of codling moth (Cydia pomonella), colorado potato beetle (Leptinotarsa decemlineata) and european grapevine moth (Lobesia botrana), http://www.dvrs.bf.uni-lj.si/spvr/2009/07bassi_09.pdf. The remarkably favourable toxicity profile of chlorantraniliprole, combined with the low use rates, provides large margins of safety for consumers and agricultural workers. Coragen(R) demonstrated excellent performance on codling moth and other chewing pests, stability of performance across the different conditions and minimal impact on, Plant Protection Society of Slovenia; Chamber of Agriculture and Forestry of Slovenia, "Chlorantraniliprole (DPX-E2Y45, Rynaxypyr(R), Coragen(R)), a new diamide inseticide for control of codling moth (Cydia pomonella), colorado potato beetle (Leptinotarsa decemlineata) and european grapevine moth (Lobesia botrana)"@eng, "Klorantranilprol (DPX-E2Y45, Rynaxypyr(R), Coragen(R)), nov diamidni insekticid za zatiranje jabolcnega zavijaca koloradskega hrosca (Leptinotarsa decemlineata) in krizastega grozdnega sukaca (Lobesia botrana)"@esp, "Lectures and papers presented at the 9th Slovenian Conference on Plant Protection, Maek, J..- Ljubljana (Slovenia): Plant Protection Society of Slovenia; Chamber of Agriculture and Forestry of Slovenia, 2009. An absence of an alert does not imply the substance has no implications for human health, biodiversity or the environment but just that we do not have the data to form a judgement. Exhibits larvicidal activity as an orally ingested toxicant by targeting and disrupting the Ca2+ balance; Ryanodine receptor modulator. DuPont says the collaboration with Arysta increases the companys Rynaxypyr investment value, and more importantly will provide growers with more tools for effective insect management. A = EU regulatory and evaluation data as published by EC, EFSA (RAR, DAR & Conclusion dossiers), EMA (e.g. (2016) An international database for pesticide risk assessments and management. Arysta says combining Rynaxypyr with acetamiprid provides several benefits: Long-term agreement allows Arysta LifeScience to combine DuPont's Rynaxypyr insect control to create novel insecticidal formulations. Whereas the new mode of action makes chlorantraniliprole a valuable option for IRM (Insecticide Resistance Management) strategies, safety to key beneficial arthropods and honeybees confer a strong fit within IPM (Integrated Production Management) programs. Extensively tested in the field since 2002, it is registered or next to market introduction in the majority of agricultural countries worldwide. pollinators, beneficial insects and predatory mites. By activating the insect ryanodine receptors (RyRs) it stimulates the release and depletion of intracellular calcium stores from the sarcoplasmic reticulum of muscle cells, causing impaired muscle regulation, paralysis and ultimately death of sensitive species (Cordova et al. It has very low toxicity for mammals (both acute and chronic), high intrinsic activity on target pests, strong ovi-larvicidal and larvicidal properties, long lasting crop protection and no cross-resistance to any existing insecticide. Premix formulations will be designed for a broader spectrum of pests than straight Rynaxypyr products. 3-bromo-N-[4-chloro-2-methyl-6-(methylcarbamoyl)phenyl]-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamide, 3-bromo-4'-chloro-1-(3-chloro-2-pyridyl)-2'-methyl-6'-(methylcarbamoyl)pyrazole-5-carboxanilide, 3-bromo-N-[4-chloro-2-methyl-6-[(methylamino)carbonyl]phenyl]-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxamide, Relevant Environmental Water Quality Standards, Herbicide Resistance Classification (HRAC), Herbicide Resistance Classification (WSSA), Insecticide Resistance Classification (IRAC), Fungicide Resistance Classification (FRAC), Example manufacturers & suppliers of products using this active now or historically, Usually supplied as a suspension concentrate or as water dispersible granules, Source; quality score; and other information, Solubility - In organic solvents at 20 C (mg l), Octanol-water partition coefficient at pH 7, 20 C, Observed in metabolism and farm animal feeding studies, Henry's law constant at 25 C (Pa m mol), Acidic solution: no absorption max >200nm, 290nm = 3941, EU dossier lab studies DT range 270-1163 days, DT range 742-2205 days, Field studies DT range 123-561 days, DT range 404-5628 days; Manufacturers published data gives DT between 3-12 months, shorter in the presence of crop cover, Dissipation rate RL on and in plant matrix, Published literature RL range 2.2-9.9 days, n=7, Aqueous hydrolysis DT (days) at 20 C and pH 7, pH 4: stable at 25 C; pH 9: unstable at 25 C, SCI-GROW groundwater index (g l) for a 1 kg ha or 1 l ha application rate, Potential for particle bound transport index, 3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-carboxylic acid (Ref: IN-DBC80), 3-bromo-1H-pyrazole-3-carboxylic acid (Ref: IN-EVK64), N-(2-(aminocarbonyl_4-4chloro-6-methylphenyl)-3-bromo-1-(3-chloro-2-pyridinyl)IH-pyrazole-5-carboxamide (Ref: IN-F9N04), 2-(((3-bromo-1-(3-chloro-2-pyridinyl)-1H-pyrazole-5-yl)carbonyl)amino)-5-chloro-3-methylbenzoic acid (Ref: IN-GKQ52), 3-bromo-N-(4-chloro020((hydroxymethyl)amino)carbonyl)-6-methylphenyl)-1-)3-chloro-2-pyridinyl)-1H-pyrazole-5-carboximide (Ref: IN-H2H20), Mammals - Chronic 21d NOAEL (mg kg bw d), Birds - Chronic 21d NOEL (mg kg bw d), Earthworms - Chronic NOEC, reproduction (mg kg), Nitrogen mineralisation: No significant adverse effect, Contact acute LD (worst case from 24, 48 and 72 hour values - g bee), Oral acute LD (worst case from 24, 48 and 72 hour values - g bee), Unknown mode acute LD (worst case from 24, 48 and 72 hour values - g bee), Acute LD (worst case from 24, 48 and 72 hour values - g insect), Beneficial insects (Ladybirds) as Mortality LR g ha, Beneficial insects (Parasitic wasps) as Mortality LR g ha, Beneficial insects (Predatory mites) as Mortality LR g ha, Aquatic invertebrates - Acute 48 hour EC (mg l), Aquatic invertebrates - Chronic 21 day NOEC (mg l), Aquatic crustaceans - Acute 96 hour LC (mg l), Sediment dwelling organisms - Acute 96 hour LC (mg l), Sediment dwelling organisms - Chronic 28 day NOEC, static, water (mg l), Sediment dwelling organisms - Chronic 28 day NOEC, sediment (mg kg), Aquatic plants - Acute 7 day EC, biomass (mg l), Algae - Acute 72 hour EC, growth (mg l), Algae - Chronic 96 hour NOEC, growth (mg l), Threshold of Toxicological Concern (Cramer Class), Mammals - Dermal LD (mg kg body weight), ADI - Acceptable Daily Intake (mg kg bw day), ARfD - Acute Reference Dose (mg kg bw day), AAOEL - Acute Acceptable Operator Exposure Level (mg kg bw day), AOEL - Acceptable Operator Exposure Level - Systemic (mg kg bw day), GB MRL modified for pulses April 2021 - see UK HSE website, Mammalian dose elimination route and rate. Extensively tested in the field since 2002, it is registered or next to market introduction in the majority of agricultural countries worldwide. Controls pests resistant to other products.

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